
Saffron Tolerability: What 102 Clinical Trials Show
The short answer Saffron was generally well tolerated in most of the clinical studies reviewed. A systematic review published in 2026 examined 102 clinical trials…
The Saffron Academy brings together in-depth articles, analyses and practical insights on saffron — from quality and ISO standards to its compounds and uses, research, culture and modern cooking.

The short answer Saffron was generally well tolerated in most of the clinical studies reviewed. A systematic review published in 2026 examined 102 clinical trials…

Can saffron help with fatty liver disease? A preclinical study published in 2026 provides new evidence that crocin II, a naturally occurring bioactive constituent of…
Can saffron help with depressive symptoms? Several randomised, placebo-controlled studies suggest that standardised saffron extracts may improve mood, stress and, in some studies, sleep quality…

Care for children with attention-deficit/hyperactivity disorder (ADHD) can include behavioural support and, depending on age, symptoms and individual circumstances, medicines such as methylphenidate. These approaches…

Saffron and cholesterol may initially seem unrelated. Saffron is best known as a spice, while cholesterol is closely associated with cardiovascular health. Scientific interest in…

Saffron in pregnancy raises two different questions: a small amount used to season food, and a concentrated product taken for a health effect. Evidence about…

Saffron and anxiety is an active research topic, but the evidence is mixed and depends on the preparation and population studied. Results from a particular…

Feeling tense, restless or mentally overloaded can make it difficult to switch off. Saffron has attracted scientific interest in this area, but the evidence needs…

Saffron and mental wellbeing are an active area of research. People often ask whether the spice can improve mood, influence serotonin or help with stress….

Saffron tea can be a fragrant way to pause at the end of the day. If you are considering it for sleep, keep the culinary…